Molecular Pathology & Cytogenetics

A Cytogenetics Department specializes in studying chromosome structure and function to diagnose genetic disorders, cancer diagnostics (leukemia), and congenital abnormalities. These labs utilize techniques like karyotyping, FISH (Fluorescent In-situ Hybridization).

Our department specializes in utilizing cutting-edge Cytogenetics technologies for a wide range of applications, including:

A. Chromosomal autosomal abnormalities

• Sex chromosome abnormalities
•  Primary amenorrhea
•  Absent secondary sexual characteristics
•  Short stature
•  Infertility
•  Problem in sexual intercourse
•  Ambiguous genetalia
• Couple with recurrent abortions
• Couple with congenitally abnormal kid’s.
• Cytogenetics study for Down’s syndrome
• Cytogenetics study for Down’s syndrome Variations (Translocation, mosaic)
• Cytogenetics study for Turner’s syndrome
• Cytogenetics study for Turner’s syndrome Variations (mosaic, iso chromosome)
• Cytogenetics study for Patau’s syndrome
• Cytogenetics study for Edward’s syndrome
• Cytogenetics study for Kline filter’s syndrome
• Cytogenetic study for Kline filter’s syndrome Variation(mosaic)
• Screening for Fanconi’s anemia or Chromosomal Breakage study
• Acute myeloid leukemia cytogenetics study(M0-M7)
• Acute lymphoblastic leukemia cytogenetics study (ALL1-ALL3)
• Myelodysplastic syndrome cytogenetics (MDS)All types
• Chronic myeloid leukemia cytogenetics study (CML)
• Erythroid hyperplasia cytogenetics study
• Invasive ductal carcinoma (Her2 by FISH)
• Invasive breast carcinoma (Her2 by FISH)
• Glioma 1p/19q co-deletion (Brain tissue by FISH)

Technologies Used

We employ a variety of advanced technologies, including:

• Conventional cytogenetics study
• Karyotyping Advance Cytovision software
•  Fluorescent In-situ Hybridization (FISH)

Current Parameters

Our current parameters cover a broad spectrum of Cytogenetics analyses, including:

• Chromosomal Analysis/Karyotyping from Blood (Test Code: 3519)
•  Cytogenetic Study for Hematological Malignancies from Bone Marrow or Peripheral Blood (Test Code: 3528)
• Chromosomal Breakage Analysis for Fanconi’s Anemia (Test Code: 1384)
•  BCR-ABL Fusion Detection by FISH (Test Code: 3531)
•  PML-RARA Fusion Detection by FISH (Test Code: 3530)
•  HER2 Amplification Detection by FISH (Test Code: 3485)
•  TP53 Gene Mutation Detection by FISH (Test Code: 5544)
•  1p/19q co-deletion Detection by FISH (Test Code: 2123)