Serum AST (SGOT)

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

Purpose of the Test

To detect liver damage

When this test is required

An AST blood test is usually requested alongside several other tests to help evaluate a patient who has symptoms of a liver disorder. Some of these symptoms include jaundice (yellowing of the eyes and skin), dark urine, nausea, vomiting, abdominal swelling, unusual weight gain, and abdominal pain. AST can also be requested, either by itself or with other tests, for: persons who might have been exposed to hepatitis viruses, those who drink too much alcohol, persons who have a history of liver disease in their family, or persons taking drugs that can occasionally damage the liver.Individuals who have mild symptoms, such as tiredness, may have AST measured to make sure they do not have long-term (chronic) liver disease. AST is often measured to monitor treatment of persons with liver disease, and may be requested either in isolation or alongside other tests.

What the Test Detects

AST is an enzyme found mostly in the heart and liver and to a lesser extent in skeletal muscle. When heart, liver or muscle cells are injured, they release AST into the bloodstream.See MoreSee Less

Preparation for the Test

None

Sample Requirements

A blood sample taken from a vein in your arm

Additional Notes

An injection of medicine into muscle tissue, or even strenuous exercise, may increase AST concentrations within the bloodstream. In rare instances, some drugs can damage the liver or muscle, increasing AST concentrations. This is true of both prescription drugs and some ‘natural’ or herbal health products. If your doctor finds that you have high levels of AST, tell him or her about all the drugs and health products you are taking.

Selected Tests