Phospholipid Syndrome Profile

Specimen Required

PT Vial and 4 cc Clotted Blood

Fasting Required

Purpose of the Test

The phospholipid syndrome profile is ordered when APS is suspected in a person with symptoms such as recurrent blood clots, miscarriages, or other complications related to blood clotting. The test can also be ordered to monitor the condition in someone who has already been diagnosed with APS.

When this test is required

The phospholipid syndrome profile is typically ordered by a healthcare provider when APS is suspected in someone with symptoms such as recurrent blood clots, stroke, or pregnancy complications. The tests may also be ordered periodically to monitor the condition in someone who has already been diagnosed with APS.

What the Test Detects

The Phospholipid Syndrome Profile includes tests for three types of antibodies:Lupus Anticoagulant (LA) – an antibody that interferes with blood clotting and can increase the risk of abnormal clot formation.Beta-2 Glycoprotein 1 (B2GP1) Antibody – an antibody that can bind to phospholipids and increase the risk of blood clots.Cardiolipin Antibody (CL) – an antibody that can bind to cardiolipin, a phospholipid found in many tissues in the body, and increase the risk of blood clots.

Preparation for the Test

There is no specific test preparation needed for the phospholipid syndrome profile. However, it is important to inform the healthcare provider if the person being tested is taking any medications that may affect blood clotting, as these medications can affect the results of the test. It is also important to follow any instructions provided by the healthcare provider regarding fasting or avoiding certain foods or medications before the test.

Sample Requirements

The phospholipid syndrome profile typically requires a blood sample. The sample may be drawn from a vein in the arm or from a fingerstick.

Additional Notes

The presence of these antibodies does not always mean that a person has APS. Other factors, such as infections, medications, or other autoimmune disorders, can also cause positive test results. Therefore, the test results should be interpreted by a healthcare provider in the context of the person’s medical history, symptoms, and other laboratory tests. It is also important to note that the phospholipid syndrome profile is not a routine screening test and is only ordered when APS is suspected or diagnosed

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