HLA Class II Tissue Typing for Patient

Specimen Required

Fasting Required

Purpose of the Test

HLA tissue typing (Class II) is a test used to determine an individual’s human leukocyte antigen (HLA) genotype, specifically for the Class II HLA genes. The HLA system plays an important role in the immune system and is involved in organ transplantation, autoimmune diseases, and certain infections.

When this test is required

The test is typically ordered when an individual needs an organ or tissue transplant, or when a healthcare provider suspects an individual has an autoimmune disease.

What the Test Detects

The test analyzes the HLA genes, specifically the Class II HLA genes, which are involved in presenting antigens to the immune system. The test looks for specific variations in these genes, which can help determine the individual’s HLA type.

Preparation for the Test

There is typically no specific preparation required for this test, but individuals should inform their healthcare provider of any medications they are taking, including over-the-counter and herbal supplements.

Sample Requirements

A blood sample is required for this test, as it contains the DNA needed for analysis.

Additional Notes

It is important to note that the HLA system is complex, and the results of this test are just one factor that is considered when evaluating compatibility for organ and tissue transplantation. The healthcare provider will consider other factors, such as the individual’s overall health and the type and severity of the disease, when making treatment decisions.

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