Before a TRUS procedure, patients may be instructed to avoid eating or drinking for a certain period of time, and may need to undergo a bowel preparation to empty the rectum. Patients should also inform their healthcare provider if they have any medical conditions or take any medications that may affect the procedure. As with any medical procedure, there are some risks associated with TRUS, including infection, bleeding, and discomfort. However, these risks are generally low, and most patients tolerate the procedure well.