Serum Total Protein

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

Purpose of the Test

Mostly forms a part of a liver function test profile, and not often requested in isolation. It can be used to calculate globulin which may indicate activation or depletion of immune system (immunoglobulin). Can help indicate certain liver, kidney disorders and several other diseases.

When this test is required

Total protein is usually measured along with several other tests when the liver is being tested.

What the Test Detects

The total protein test is a rough measure of all of the proteins in the plasma portion of your blood. Proteins are important building blocks of all cells and tissues. Total protein measures the combined amount of proteins the two major two classes of which are albumin and immunoglobulin. Albumin is a carrier of many small molecules, but its main purpose is to keep fluid from leaking out of blood vessels, while immunoglobulin proteins are antibodies. To a much lesser extent enzymes and more than 500 other proteins contribute to the total protein.See MoreSee Less

Preparation for the Test

None

Sample Requirements

A blood taken from a vein

Additional Notes

Prolonged application of a tourniquet during blood collection can increase total protein levels. Drugs that may increase protein levels include anabolic steroids, androgens, growth hormone, insulin, and progesterone. Drugs that may decrease protein levels include oestrogens.

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