Serum RPR/VDRL

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

Purpose of the Test

Serum RPR (Rapid Plasma Reagin) and VDRL (Venereal Disease Research Laboratory) tests are used to screen for syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum.

When this test is required

These tests may be requested when a person shows signs or symptoms of syphilis, such as genital sores, skin rash, fever, swollen lymph nodes, and sore throat. They may also be ordered as part of routine screening during pregnancy or as part of a sexual health check-up.

What the Test Detects

These tests detect the presence of antibodies produced by the body in response to a syphilis infection. The RPR test measures antibodies in the blood that react with a substance called cardiolipin. The VDRL test measures antibodies that react with a substance called reagin.

Preparation for the Test

No special preparation is required for these tests.

Sample Requirements

The test requires a blood sample, which is usually drawn from a vein in the arm.

Additional Notes

It is important to get treated promptly if syphilis is detected, as it can cause serious health problems if left untreated. It is also important to follow up with your healthcare provider for further testing and treatment if you have a positive test result.

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