Serum Kappa Lambda Ratio

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

Purpose of the Test

The serum kappa/lambda ratio test is used to evaluate and monitor certain blood cell disorders, such as multiple myeloma and other plasma cell dyscrasias. It compares the levels of kappa light chains and lambda light chains, which are proteins produced by plasma cells, in the blood.

When this test is required

The test may be requested if someone is showing symptoms of a blood cell disorder or if a healthcare provider suspects the presence of a disorder based on other tests and evaluations.

What the Test Detects

The serum kappa/lambda ratio test measures the levels of kappa light chains and lambda light chains, which are proteins produced by plasma cells, in the blood. The ratio of these proteins can help diagnose and monitor certain blood cell disorders, such as multiple myeloma and other plasma cell dyscrasias.

Preparation for the Test

There is no specific preparation needed for the test. However, it may be recommended to fast for a certain period of time prior to the test, depending on the healthcare provider’s instructions.

Sample Requirements

The test requires a blood sample, which is usually drawn from a vein in the arm.

Additional Notes

It is important to note that the serum kappa/lambda ratio test is not specific to any one disorder and should be used in conjunction with other tests and evaluations to make a diagnosis. It is also important to discuss the test results with a healthcare provider to understand their implications and how they will be used in treatment planning.

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