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Serum GGT

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

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Purpose of the Test

To screen for liver disease and to help your doctor tell whether a raised concentration of alkaline phosphatase (ALP) in the bloodstream is due to liver or bone disease

When this test is required

A doctor usually requests GGT along with other tests to evaluate a person who has signs or symptoms that suggest liver disease. Some of the symptoms of liver injury include jaundice, nausea, vomiting, abdominal (around the stomach area) swelling, abdominal pain, pruritus (severe itching), and tiredness.GGT is increased in most diseases that cause damage to the liver or bile ducts, but is usually not helpful in distinguishing between different causes of liver damage as a single test. However there are studies that indicate GGT can be used together with other markers as diagnostic scores to predict the presence of liver fibrosis and also for non-alcoholic fatty liver disease. In people with a history of alcohol abuse who are undergoing treatment, GGT may be used to check that the person is following the treatment program properly.

What the Test Detects

Preparation for the Test

No test preparation is needed

Sample Requirements

A blood sample taken from a vein in your arm

Additional Notes

Alcohol consumed within 24 hours of your GGT test may cause a temporary increase in the GGT result, if you consume alcohol regularly. If this occurs, your doctor may want to repeat the test to verify the result.Smoking may also increase GGT concentrations.Levels of GGT increase with age in women, but not in men, and are always somewhat higher in men than in women.Several drugs increase (induce) the concentration of GGT in the blood. The increases do not indicate damage to the liver. Please inform your doctor of any prescription or non prescription drugs that you are taking.