Serum Brucella IgM

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

Purpose of the Test

This test is ordered to help diagnose brucellosis, which is a bacterial infection that can cause flu-like symptoms, such as fever, joint pain, and fatigue. The test is also used to monitor the effectiveness of treatment for brucellosis.

When this test is required

The test is usually requested if a person has symptoms that suggest a brucellosis infection, such as a fever that lasts for several days, muscle pain, or swollen lymph nodes. It may also be ordered if a person has been exposed to Brucella bacteria, such as through contact with infected animals or consumption of contaminated food products.

What the Test Detects

The presence of IgM antibodies against Brucella bacteria indicates a recent or active infection with Brucella. IgM antibodies are the first antibodies produced by the immune system in response to an infection, and they are typically detectable in the blood within 1-2 weeks of infection. IgM antibodies usually disappear within a few months of the infection, although they may persist for longer in some cases.

Preparation for the Test

There is usually no special preparation needed for a serum Brucella IgM test. However, you should let your healthcare provider know about any medications you are taking, as some medications can affect the results of the test. If you have had a recent transfusion, you may need to wait a certain amount of time before having the test done. Your healthcare provider will provide specific instructions if any preparation is necessary.

Sample Requirements

To perform the test, a healthcare provider will need to collect a blood sample from a vein in your arm using a needle.

Additional Notes

It is important to note that the serum Brucella IgM test is not always definitive, and additional testing may be required to confirm a diagnosis of brucellosis. False-positive results can occur in individuals who have been vaccinated against Brucella or who have previously been infected with a similar bacteria. False-negative results can occur if the test is performed too late in the course of the infection, after the IgM antibodies have already disappeared from the blood.

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