Albumin is made in the liver and it is the most abundant protein in the blood plasma. It keeps fluid from leaking out of blood vessels; nourishes tissues; and carries hormones, vitamins, drugs, and ions like calcium throughout the body. Albumin concentration in the blood is sensitive to liver damage. The concentration of albumin in the blood drops when the liver is severely damaged or with a type of kidney disease called ‘nephrotic syndrome, or if a person experiences severe inflammation in the body, or with shock. The albumin concentration in the blood increases when a person is dehydrated.See MoreSee Less