A qualitative screening for unknown compounds by GC-MS (Gas Chromatography-Mass Spectrometry) is a laboratory test that is used to identify unknown substances in a sample. This test is commonly used in forensic toxicology, environmental analysis, and industrial hygiene.
When this test is required
The test may be requested by a regulatory agency, a healthcare provider, or an employer.
What the Test Detects
The test uses GC-MS technology to separate and detect the individual components of a sample. The sample is introduced into a gas chromatograph, where it is separated into its individual components based on their physical and chemical properties. The separated compounds are then introduced into a mass spectrometer, where they are ionized and analyzed to identify their molecular structure.
Preparation for the Test
Sample preparation requirements will vary depending on the nature of the substance being tested. Typically, the sample is extracted, purified, and concentrated to isolate the analyte of interest prior to analysis.
Sample Requirements
A sample of the substance or sample matrix is required for the test. The sample should be collected and preserved according to the appropriate protocols for the specific type of substance being tested.
Additional Notes
It is important to note that GC-MS testing is a highly specialized laboratory technique and should only be performed by trained professionals in a clinical, forensic, or environmental laboratory setting.
