Drugs such as ACE inhibitors, beta-blockers and diuretics can decrease BNP and NT-proBNP concentrations. It is important to inform your healthcare professional if you are taking these medications, so the test result can be interpreted correctly. Do not stop taking these medications without consulting with your healthcare professional.BNP and NT-proBNP results provide the same information for your doctor but results for the different tests cannot be compared directly, and measurements should not be interchanged.Increased levels of BNP and NT-proBNP are seen in patients with chronic kidney disease (CKD).