The test is typically requested when a healthcare provider suspects that a patient may have a pericardial infection caused by a fungus. This suspicion may arise from symptoms such as chest pain, shortness of breath, and fever, or from other diagnostic tests, such as imaging studies or blood tests. The test may also be requested for patients who have a high risk of developing a pericardial fungal infection, such as those with weakened immune systems or who have recently undergone cardiac surgery.