LDH (lactate dehydrogenase) in cerebrospinal fluid (CSF) is a test that may be used to help diagnose and monitor conditions affecting the brain and nervous system, such as meningitis, encephalitis, and other neurological disorders.
When this test is required
The test may be requested if a healthcare practitioner suspects that a person has an infection or inflammation of the brain or spinal cord, or if they have other symptoms suggestive of a neurological disorder.
What the Test Detects
The test measures the level of LDH in the CSF. LDH is an enzyme found in many body tissues, including the brain and spinal cord. Increased levels of LDH in the CSF may indicate damage or inflammation of these tissues.
Preparation for the Test
The patient should inform their healthcare provider of any medications they are taking and any medical conditions they have that may affect the test.
Sample Requirements
The test requires a sample of cerebrospinal fluid, which is obtained through a procedure called a lumbar puncture (also known as a spinal tap).
Additional Notes
A lumbar puncture is a procedure that carries some risks, including headache, infection, and bleeding. The patient should discuss the risks and benefits of the procedure with their healthcare provider before undergoing the test.
