India Ink Preparation

Specimen Required

CSF

Fasting Required

Purpose of the Test

The India ink preparation is typically ordered when a healthcare provider suspects that a patient may have a fungal infection, particularly one caused by Cryptococcus neoformans. This type of infection can occur in people with weakened immune systems, such as those with HIV/AIDS or who have had an organ transplant.

When this test is required

The test may be requested when a healthcare provider suspects that a patient may have a fungal infection, particularly one caused by Cryptococcus neoformans.

What the Test Detects

The India ink preparation test detects the presence of the capsule surrounding certain fungi, such as Cryptococcus neoformans, in a sample of fluid or tissue. The capsule is composed of polysaccharides, which are substances that can be visualized using a special stain called India ink.

Preparation for the Test

There is typically no special preparation required for this test.

Sample Requirements

The test requires a sample of fluid or tissue, such as cerebrospinal fluid, pleural fluid, or lung tissue.

Additional Notes

The India ink preparation test is just one of several tests that may be used to diagnose a fungal infection. Other tests may include fungal culture, antigen testing, and PCR testing.

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