Immuno-Chemistry (Bone Marrow Trephine) with History

Specimen Required

EDTA+Bone Marrow Aspirate Slides+Trephine biopsy

Fasting Required

Purpose of the Test

This test is usually performed when a healthcare provider suspects a bone marrow disorder, such as leukemia or lymphoma, or when a person experiences symptoms such as fatigue, weakness, unexplained weight loss, or abnormal bleeding or bruising. The test can also be used to monitor the progression of bone marrow disorders and assess the effectiveness of treatment.

When this test is required

The test is usually requested when a healthcare provider suspects a bone marrow disorder based on symptoms or abnormal blood tests. The test may also be ordered as part of routine monitoring for people with known bone marrow disorders, or to assess the effectiveness of treatment.

What the Test Detects

Immunochemistry (Bone Marrow Trephine) is a test that examines a small sample of bone marrow tissue under a microscope to evaluate the presence and characteristics of various types of cells, such as red blood cells, white blood cells, and platelets. The test also involves using specific antibodies to identify certain proteins or markers on the surface of cells, which can help identify abnormal cells or determine the type of bone marrow disorder.

Preparation for the Test

Before the test, the healthcare provider will give instructions on how to prepare, which may include fasting for a certain period of time before the procedure. The provider will also discuss any medications that the person may need to stop taking temporarily before the test, such as blood thinners. It is important to inform the provider of any medications or medical conditions the person has before the test. Additionally, the person should arrange for someone to drive them home after the procedure, as they may feel drowsy or experience discomfort after the procedure.

Sample Requirements

The test requires a small sample of bone marrow tissue, typically obtained through a bone marrow biopsy. During the procedure, a thin, hollow needle is inserted into the bone, usually the hip bone, to extract a small amount of bone marrow tissue.

Additional Notes

Bone marrow trephine is an invasive procedure that involves inserting a needle into the bone to obtain a sample of bone marrow tissue. The procedure may cause some discomfort, bruising, or bleeding at the site. The healthcare provider will give instructions on how to prepare for the test and what to expect during and after the procedure. It is important to inform the healthcare provider of any medications or medical conditions that the person has, as they may affect the test results or the ability to perform the procedure safely.

Selected Tests