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EBV by PCR (Quantitative)

Specimen Required

9cc EDTA Blood (3 CBC Vials)

Fasting Required

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Purpose of the Test

The EBV by PCR (quantitative) test is used to detect and measure the amount of Epstein-Barr virus (EBV) DNA in the blood. It is primarily used to help diagnose and monitor certain EBV-associated conditions, such as infectious mononucleosis and certain types of cancer.

When this test is required

The test is usually requested when a person shows symptoms of an EBV-associated condition, such as fever, sore throat, swollen lymph nodes, and fatigue. It may also be requested to monitor the progression of the disease or to evaluate the effectiveness of treatment.

What the Test Detects

The test looks for the presence and amount of EBV DNA in the blood using the polymerase chain reaction (PCR) technique. PCR amplifies small amounts of viral DNA to detectable levels, allowing for accurate and sensitive detection of EBV in the blood.

Preparation for the Test

There is no specific test preparation needed. However, it is recommended to inform the healthcare provider about any medications being taken before the test.

Sample Requirements

The test requires a blood sample, which is usually drawn from a vein in the arm. Sometimes, other types of samples such as cerebrospinal fluid or tissue biopsy may be used.

Additional Notes

The EBV by PCR (quantitative) test is a highly sensitive and specific test for detecting EBV DNA in the blood. However, it cannot differentiate between active and inactive infections, and a positive test result does not always indicate an ongoing disease. It is recommended to discuss the test results with a healthcare provider for further guidance and treatment options.