A bone profile test may be requested if you have symptoms of bone disease, such as bone pain or fractures, or if you have risk factors for bone loss, such as age, menopause, a family history of osteoporosis, smoking, alcohol consumption, or a sedentary lifestyle. The test may also be requested if you are undergoing treatment for a bone-related condition or if your healthcare provider suspects that you have a hormonal imbalance affecting bone health.