BK polyomavirus (BKV) is a virus that commonly infects humans without causing any symptoms. However, in people with weakened immune systems, such as transplant recipients, the virus can become active and cause serious infections, including nephropathy (kidney disease) and cystitis (bladder inflammation). The BK polyomavirus (quantitative) test is ordered to monitor the levels of the virus in the blood of transplant patients and to help diagnose and manage BKV-associated nephropathy.