Anti-Thyroid Antibodies Profile (ATA)

Specimen Required

3-5cc Clotted Blood or Serum

Fasting Required

Purpose of the Test

An Anti-Thyroid Antibodies Profile (ATA) test is used to diagnose autoimmune thyroid diseases, such as Hashimoto’s thyroiditis and Graves’ disease. The test measures the levels of different antibodies that are produced by the immune system against the thyroid gland, including thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb). High levels of these antibodies can indicate that the immune system is attacking the thyroid gland, leading to an underactive or overactive thyroid.

When this test is required

The ATA test is usually requested when a person has symptoms of a thyroid disorder, such as fatigue, weight gain, hair loss, or irregular heartbeat. It may also be ordered when a person has an enlarged thyroid gland (goiter) or when there is a family history of autoimmune thyroid disease.

What the Test Detects

An Anti-Thyroid Antibodies Profile (ATA) test measures the levels of different antibodies that are produced by the immune system against the thyroid gland. The test typically includes the measurement of thyroid peroxidase antibodies (TPOAb) and thyroglobulin antibodies (TgAb). These antibodies are produced when the immune system mistakenly attacks the thyroid gland, leading to thyroid dysfunction and autoimmune thyroid diseases such as Hashimoto’s thyroiditis and Graves’ disease.

Preparation for the Test

There is no specific preparation required for this test. However, the healthcare provider may advise the person to avoid certain medications, such as thyroid hormones or steroids, that can affect the test results. The person should inform the healthcare provider of any medications or supplements they are taking before the test.

Sample Requirements

The test requires a blood sample, which is usually taken from a vein in the arm.

Additional Notes

The ATA test is a useful tool in the diagnosis and management of autoimmune thyroid diseases. However, a positive result does not always mean that a person has a thyroid disorder. Other factors, such as pregnancy or recent viral infections, can also cause temporary increases in thyroid antibodies. Therefore, the test results should be interpreted in conjunction with other clinical and laboratory findings.

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