Anti Musk Antibodies (AKU)

Specimen Required

Fasting Required

Purpose of the Anti Musk Antibodies (AKU) Test

The Anti-MuSK Antibody Test (AKA) is used to diagnose Myasthenia Gravis (MG), a chronic autoimmune neuromuscular disorder. MuSK (muscle-specific tyrosine kinase) is a protein found in the muscle fibers that plays a crucial role in the communication between nerves and muscles. When antibodies against MuSK are produced by the immune system, they interfere with the normal functioning of the neuromuscular junction, leading to muscle weakness and fatigue.

When this Anti Musk Antibodies (AKU) test is required

The AKA test is requested when a person presents with symptoms of MG, and the doctor suspects a MuSK-associated form of the disease.

What the Anti Musk Antibodies (AKU) Test Detects

The AKA test measures the level of antibodies against the MuSK protein in the blood.

Preparation for the Anti Musk Antibodies (AKU) Test

No specific preparation is required for the AKA test.

Sample Requirements

The AKA test requires a blood sample.

Additional Notes

The AKA test is a valuable tool for diagnosing MG, especially in cases where the AChR antibody test is negative. A positive result on the AKA test, along with other clinical findings, can help the doctor to make a more accurate diagnosis and plan appropriate treatment. However, it is important to note that a negative AKA test result does not rule out the possibility of MuSK-associated MG, and further testing may be required.

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