It is important to collect a good quality tissue sample for accurate testing. The healthcare provider may provide instructions on how to collect the sample, including using a sterile needle or scalpel to obtain tissue from the affected area. In some cases, other tests, such as a chest X-ray or a tuberculin skin test, may also be needed to confirm a diagnosis of tuberculosis. It is important to follow the healthcare provider’s instructions for treatment and to complete the full course of antibiotics to prevent the spread of the disease and avoid the development of drug-resistant tuberculosis.